Co-located quantitative trait loci mediate resistance to Agrobacterium tumefaciens, Phytophthora cinnamomi, and P. pini in Juglans microcarpa × J. regia hybrids

Co-located quantitative trait loci mediate resistance to Agrobacterium tumefaciens, Phytophthora cinnamomi, and P. pini in Juglans microcarpa × J. regia hybrids

Soil-borne plant pathogens characterize a critical risk that undermines industrial walnut (Juglans regia) manufacturing worldwide. Crown gall, attributable to Agrobacterium tumefaciens, and Phytophthora root and crown rots, attributable to varied Phytophthora spp., are among the many most devastating walnut soil-borne ailments.
A acknowledged technique to fight soil-borne ailments is adoption of resistant rootstocks. Right here, resistance to A. tumefaciens, P. cinnamomi, and P. pini is mapped within the genome of Juglans microcarpa, a North American wild relative of cultivated walnut. Half-sib J. microcarpa mom bushes DJUG 31.01 and DJUG 31.09 had been crossed with J. regia cv. Serr, producing 353 and 400 hybrids, respectively.
Clonally propagated hybrids had been genotyped by sequencing to assemble genetic maps for the 2 populations and challenged with the three pathogens. Resistance to every of the three pathogens was mapped as a serious QTL on the lengthy arm of J. microcarpa chromosome 4D and was related to the identical haplotype, designated as haplotype b, elevating the likelihood that the 2 mom bushes had been heterozygous for a single Mendelian gene conferring resistance to all three pathogens.
The deployment of this haplotype in rootstock breeding will facilitate breeding of a walnut rootstock immune to each crown gall and Phytophthora root and crown rots.

A number of Viral Infections Detected in Phytophthora condilina by Complete and Small RNA Sequencing

Marine oomycetes have lately been proven to be concurrently contaminated by (-)ssRNA viruses of the order Bunyavirales. On this work, even greater virus variability was present in a single isolate of Phytophthora condilina, a lately described member of Phytophthora phylogenetic Clade 6a, which was remoted from brackish estuarine waters in southern Portugal.
Utilizing complete and small RNA-seq the total RdRp of 13 totally different potential novel bunya-like viruses and two full toti-like viruses had been detected. All these viruses had been efficiently confirmed by reverse transcription polymerase chain response (RT-PCR) utilizing complete RNA as template, however complementarily one of many toti-like and 5 of the bunya-like viruses had been confirmed when dsRNA was purified for RT-PCR. In our examine, complete RNA-seq was by much more environment friendly for de novo assembling of the virus sequencing however small RNA-seq confirmed greater learn numbers for many viruses.
Co-located quantitative trait loci mediate resistance to Agrobacterium tumefaciens, Phytophthora cinnamomi, and P. pini in Juglans microcarpa × J. regia hybrids
Two fundamental populations of small RNAs (21 nts and 25 nts-long) had been recognized, which had been in accordance with different Phytophthora species. To the very best of our information, that is the primary examine utilizing small RNA sequencing to determine viruses in Phytophthora spp.

Stepwise accumulation of mutations in CesA3 in Phytophthora sojae leads to rising resistance to CAA fungicides

Flumorph is a carboxylic acid amide (CAA) fungicide with excessive exercise towards oomycetes. Nonetheless, evolution to CAAs from low resistance to excessive resistance has by no means been reported. This examine investigated the premise of resistance evolution of flumorph in Phytophthora sojae.
Complete of 120 P. sojae isolates had been collected and their sensitivity to flumorph was evaluated. Though no spontaneous resistance was discovered among the many area isolates, adaptation on flumorph-amended media resulted within the collection of 5 steady mutant varieties exhibiting various levels of resistance to CAAs.
Kind I, which exhibited the bottom resistance stage, was obtained when the wild-type isolate was uncovered to a low focus of flumorph, however no resistant mutants had been obtained by direct publicity to greater concentrations. Nonetheless, the extra resistant varieties (Kind II, III, IV and V) had been obtained when Kind I had been uncovered to greater concentrations of flumorph.
Comparable outcomes had been obtained when your entire screening course of was repeated, which implied that evolution of resistance to flumorph in P. sojae could possibly be a two-step course of, the place excessive resistance phenotypes may develop regularly from low resistance ones.
Additional investigation into molecular mechanism strongly confirmed that evolution of isolates extremely immune to flumorph happens in a stepwise course of with Kind I as middleman, by means of accumulation of mutations of their goal protein of CAAs (CesA3). Collectively, our findings point out that software of low charges of flumorph in area may lead to collection of low resistance Kind I isolates, however that elevating dosage to keep up comparable ranges of management may elicit speedy evolution of extra resistant Kind II, III, IV and V isolates with stepwise accumulation of mutations in CesA3, which might render flumorph ineffective as a management technique.

20 x ELISA Wash Buffer

GR103014-20 1 L
EUR 189.6

20UL FILTER TIPS FOR P-20

TF-20 1000/pk
EUR 501.6
Description: Filter Tip; Filter Tips Pipette - Axygen

Anti-Cat Whole Serum | RWS-20

RWS-20 1.0 mL
EUR 153
Description:

Anti-Cat Whole Serum | RWS-20 | Immunology Consultants Laboratory

Host: Rabbit

Format: Whole Serum

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

3-D Life 10x CB Buffer (pH 7.2)

B20-3 600 µL
EUR 52.8

AXYGEN® GEL TRAY 20 X 20 CM FOR USE WITH 20 CM GEL BOX, UV TRANSPARENT

HGB20-20-GT 1/pk
EUR 116.4
Description: Lab Equipment; Axygen Branded EQ

DiagNano Silica-Coated Gold Nanoparticles, 20 nm

CG-20 10mL
EUR 862.8

TW-20 with 11 in. Canisters (6)

TW-20 1 Unit
EUR 1226
Description: TW-20 with 11 in. Canisters (6)

99447 DSSCT 20 X 125 W/ MARKING SPOT

99447-20 250/pk
EUR 253.2
Description: Disposable Screw Cap Culture Tubes; DSCCT's, Lab Stock

DiagNano Gold Nanoparticle Passive Conjugation Kit, 20 nm

GPK-20 1 kit
EUR 858

DiagNano Silica-Coated PEGylated Gold Nanoparticles, 20 nm

PG-20 10mL
EUR 862.8

Turbidity Std Ratio 20 NTU

CRSR-20-100 100ML
EUR 125.4

Turbidity Std Ratio 20 NTU

CRSR-20-1000 1L
EUR 557.46

Turbidity Std Ratio 20 NTU

CRSR-20-500 500ML
EUR 248.52

GCN5 highly active Recombinant Protein

90-345 2 ug
EUR 500.1
Description: GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.

TIP60 highly active Recombinant Protein

90-347 2 ug
EUR 500.1
Description: TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex is required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. TIP60 directly acetylates and activates ataxia-telangiectasia mutated (ATM). In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

PARG highly active Recombinant Protein

90-350 2 ug
EUR 500.1
Description: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.

NMNAT1 highly active Recombinant Protein

90-354 10 ug
EUR 437.1
Description: Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

NMNAT1 highly active Recombinant Protein

90-355 50 ug
EUR 619.8
Description: Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.

NMNAT3 highly active Recombinant Protein

90-356 10 ug
EUR 468.6
Description: Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.

NMNAT3 highly active Recombinant Protein

90-357 50 ug
EUR 852.9
Description: Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.

99449 DSSCT 20 X 125MM W/O MARKING SPOT

99449-20 250/pk
EUR 273.6
Description: Disposable Screw Cap Culture Tubes; DSCCT's, Lab Stock

Single channel mini-pipette (130 mm) 20 ul, autoclavable

SCMP-20 1
EUR 110.4

20 mm Decrimp head ; Level 3 High Performance Applications

ECDJ-20 EACH
EUR 295.26

20 mm Crimp head ; Level 3 High Performance Applications

ECMJ-20 EACH
EUR 295.26

Turbidity Std Non Ratio 20 NTU

CRS-20-100 100ML
EUR 118.56

Turbidity Std Non Ratio 20 NTU

CRS-20-500 500ML
EUR 235.98

Normal Cat Serum | RS-20-100ML

RS-20-100ML 100 mL
EUR 750
Description:

Normal Cat Serum | RS-20-100ML | Immunology Consultants Laboratory

Species Reactivity: Cat

Format: Serum

Product Type: Isotype Control

Antibody clonality: Polyclonal

Dual-Thickness MicroMounts, box of 20 with 20 micron aperture mounts; mounted on 18 mm rods

M2-L18SP-20 20 MOUNTS
EUR 112
Description: Dual-Thickness MicroMounts, box of 20 with 20 micron aperture mounts; mounted on 18 mm rods

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1030-20
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)

M1031-20
EUR 1546.8

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions)

M1032-20
EUR 1618.8

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions)

M1033-20
EUR 1618.8

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions)

M1034-20
EUR 1495.2

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions)

M1035-20
EUR 1495.2

TumorExoRNA? Tumor-derived exosome immunocapture and RNA extraction kit (20 reactions)

K1221-20
EUR 1462.8

Exosome binding buffer for ELISAs (20 ml)

EXOEL-BB-20 20 ml
EUR 262.8

NAD Kinase highly active Recombinant Protein

90-353 50 ug
EUR 651.3
Description: NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis.

Sulfur 20 ug/g (20 PPM) for AA and ICP 100 grams in no.2 Diesel Fuel

SDFS-20-Y 100ML
EUR 102.6

FGF-acidic Recombinant Protein

40-159-001mg 0.01 mg
EUR 311.1
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 15.8 kDa protein consisting of 140 amino acid residues.

FGF-acidic Recombinant Protein

40-159-005mg 0.05 mg
EUR 437.1
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 15.8 kDa protein consisting of 140 amino acid residues.

FGF-acidic Recombinant Protein

40-588 0.05 mg
EUR 481.2
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 15.8 kDa protein consisting of 140 amino acid residues.

FGF acidic Recombinant Protein

40-493-001mg 0.01 mg
EUR 311.1
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

FGF acidic Recombinant Protein

40-493-005mg 0.05 mg
EUR 437.1
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

FGF-acidic Recombinant Protein

40-543-001mg 0.01 mg
EUR 311.1
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

FGF-acidic Recombinant Protein

40-543-005mg 0.05 mg
EUR 437.1
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions)

M1036-20
EUR 1546.8

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions)

M1037-20
EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 20 reactions)

M1039-20
EUR 1546.8

Recombinant Human Interleukin-20/IL-20

C147-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-20/IL-20

C147-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-20/IL-20

C147-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-20/IL-20

C147-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

ExoDNAPS? Circulating and Exosome-associated DNA Extraction Kit (Human Plasma/Serum, 20 reactions)

K1230-20
EUR 861.6

ExoDNAUC? Circulating and Exosome-associated DNA Extraction Kit (Urine/Cell Media, 20 reactions)

K1231-20
EUR 861.6

Custom Anti-Peptide antibodies (peptide synthesis up to 20-aa, conjugation, 2 rabbits, ELISA)

ABPEP-20 1
EUR 1951.2

TotalExoRNA? Overall exosome immunocapture and RNA extraction kit (Biological Fluids/Cell Media, 20 reactions)

K1220-20
EUR 1462.8

DiagNano Silica-Coated Gold Nanoparticles, 20 nm, 100 OD

CG-20-100 0.25mL
EUR 926.4

20 bp random library with flanking sequence; DNA aptamer

DAL-N-20 100 ug
EUR 343.2

DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 20 nm

GCK-M-20 1 kit
EUR 908.4

DiagNano Fluorophore Labeled Gold Nanoparticles, 20 nm, Cellular Uptake

GFL-20-CU 1mL
EUR 1638

IL-20 Interleukin-20 Mouse Recombinant Protein

PROTQ9JKV9 Regular: 10ug
EUR 380.4
Description: Interleukin-20 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids and having a total molecular mass of 17,584 Dalton. The IL-20 is purified by proprietary chromatographic techniques.

IL-20 Interleukin-20 Human Recombinant Protein

PROTQ9NYY1 Regular: 10ug
EUR 380.4
Description: Interleukin-20 Human Recombinant produced in E.Coli is a single, non-glycosylated homodimeric polypeptide chain containing 2 x 153 amino acids and having a total molecular mass of 35,212 Dalton. ;The IL-20 is purified by proprietary chromatographic techniques.

CREB-binding Protein highly active Recombinant Protein

90-344 2 ug
EUR 500.1
Description: CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.

NF-kB p65 highly active Recombinant Protein

90-348 2 ug
EUR 600.9
Description: NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappaB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric p65-p50 complex is the most abundant complex. The dimers bind at kappaB sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappaB sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappaB complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappaB inhibitor (I-kappaB) family. In a conventional activation pathway, I-kappaB is phosphorylated by I-kappaB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappaB complex which translocates to the nucleus. NF-kappaB heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-kappaB p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappaB complex.

NF-kB p50 highly active Recombinant Protein

90-349 2 ug
EUR 632.4
Description: NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappaB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric p65-p50 complex is the most abundant complex. The dimers bind at kappaB sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappaB sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappaB complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappaB inhibitor (I-kappaB) family. In a conventional activation pathway, I-kappaB is phosphorylated by I-kappaB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappaB complex which translocates to the nucleus. NF-kappaB heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappaB p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3.

Recombinant Human FGF-acidic Protein

PROTP05230-2 50ug
EUR 380.4
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues.

Recombinant Murine FGF-acidic Protein

PROTP61148-2 50ug
EUR 380.4
Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

Recombinant Rat FGF-acidic Protein

PROTP61149-1 50ug
EUR 380.4
Description: FGF-acidic is one of 23 known members of the FGF family.  Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells.  FGF-acidic has the ability to signal through all the FGF receptors.  Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

DiagNano Silica-Coated PEGylated Gold Nanoparticles, 20 nm, 100 OD

PG-20-100 0.25mL
EUR 1101.6

StayBrite? Highly Stable Luciferase

7901-150
EUR 464.4

SAG Analog (highly active)

GL3544-1MG 1 mg
EUR 385.2

Sign 210x148mm Danger Highly ..

HA13051R EACH
EUR 8.64

Sign 210x148mm Danger Highly ..

HA13051S EACH
EUR 5.48

Oligo (dT)20 Coated Gold Particles

OdT(20)AuP-002-1 1 mL
EUR 462
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Oligo (dT)20 Coated Gold Particles

OdT(20)AuP-002-5 5 mL
EUR 1254
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

Recombinant Human Interleukin-20

7-01051 2µg Ask for price

Recombinant Human Interleukin-20

7-01052 10µg Ask for price

Recombinant Human Interleukin-20

7-01053 1mg Ask for price

Recombinant Mouse Interleukin-20

7-01054 2µg Ask for price

Recombinant Mouse Interleukin-20

7-01055 10µg Ask for price

Recombinant Mouse Interleukin-20

7-01056 1mg Ask for price

Recombinant Human Cytokeratin 20

7-05461 5µg Ask for price

Recombinant Human Cytokeratin 20

7-05462 20µg Ask for price

Recombinant Human Cytokeratin 20

7-05463 1mg Ask for price

FGF-20 Recombinant Protein

40-185-0003mg 0.003 mg
EUR 311.1
Description: FGF-20 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through the FGFR 2c and 3c and is expressed during limb and brain development. Recombinant human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues.

FGF-20 Recombinant Protein

40-185-0015mg 0.015 mg
EUR 437.1
Description: FGF-20 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through the FGFR 2c and 3c and is expressed during limb and brain development. Recombinant human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues.

FGF-20, human recombinant

4589-100
EUR 966

FGF-20, human recombinant

4589-1000
EUR 4627.2

IL-20, human recombinant

4548-10
EUR 385.2

IL-20, human recombinant

4548-1000
EUR 7100.4

IL-20, human recombinant

4548-50
EUR 1123.2

IL-20, murine recombinant

4549-10
EUR 339.6

IL-20, mouse recombinant

4549-1000
EUR 10238.4

IL-20 Recombinant Protein

40-265-0002mg 0.002 mg
EUR 311.1
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

IL-20 Recombinant Protein

40-265-001mg 0.01 mg
EUR 437.1
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

IL-20 Recombinant Protein

91-129 0.05 mg
EUR 821.4
Description: Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 R alpha and IL-20 R beta . The second is composed of IL-22 R and IL-20 R beta . Whereas the IL-22 R/IL-20 R beta complex is shared with IL-24, the IL-20 R alpha/IL-20 R beta complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF- alpha and MCP-1. Initial functional studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neonatal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.

Recombinant Human Interleukin-20

CC069-002 2ug
EUR 351.6

Recombinant Human Interleukin-20

CC069-010 10ug
EUR 489.6

Recombinant Human Interleukin-20

CC069-101 1mg
EUR 10752

Recombinant Mouse Interleukin-20

CC078-002 2ug
EUR 351.6

Recombinant Mouse Interleukin-20

CC078-010 10ug
EUR 489.6

Recombinant Mouse Interleukin-20

CC078-101 1mg
EUR 12372

Recombinant Mucin 20 (MUC20)

4-RPA995Ra01
  • EUR 625.34
  • EUR 290.40
  • EUR 2015.04
  • EUR 751.68
  • EUR 1383.36
  • EUR 494.40
  • EUR 4857.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Mucin 20 expressed in: E.coli

Recombinant Keratin 20 (KRT20)

4-RPB240Hu01
  • EUR 560.83
  • EUR 273.60
  • EUR 1773.12
  • EUR 671.04
  • EUR 1222.08
  • EUR 451.20
  • EUR 4252.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Keratin 20 expressed in: E.coli

Recombinant Keratin 20 (KRT20)

4-RPB240Mu01
  • EUR 528.58
  • EUR 265.20
  • EUR 1652.16
  • EUR 630.72
  • EUR 1141.44
  • EUR 429.60
  • EUR 3950.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Keratin 20 expressed in: E.coli

Recombinant Keratin 20 (KRT20)

4-RPB240Ra01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Keratin 20 expressed in: E.coli

Recombinant Interleukin 20 (IL20)

4-RPC058Hu01
  • EUR 687.71
  • EUR 307.20
  • EUR 2248.90
  • EUR 829.63
  • EUR 1539.26
  • EUR 535.20
  • EUR 5442.24
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Interleukin 20 expressed in: E.coli

Recombinant Cadherin 20 (CDH20)

4-RPG427Hu01
  • EUR 711.36
  • EUR 314.40
  • EUR 2337.60
  • EUR 859.20
  • EUR 1598.40
  • EUR 552.00
  • EUR 5664.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Cadherin 20 expressed in: E.coli

Recombinant Protocadherin 20 (PCDH20)

4-RPE100Hu01
  • EUR 560.83
  • EUR 273.60
  • EUR 1773.12
  • EUR 671.04
  • EUR 1222.08
  • EUR 451.20
  • EUR 4252.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Protocadherin 20 expressed in: E.coli

BAFF, Soluble 60-mer highly active Recombinant Protein

90-294 10 ug
EUR 537.9
Description: BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers. Processed human BAFF can either remain as a trimer, which is usual for TNF family ligands or assemble into 60-mer composed of 20 trimers. Mouse BAFF 60-mer has been identified in the serum of BAFF transgenic mice. Oligomerization of BAFF 3-mer into 60-mer in human BAFF is prevented by mutation of His218, a residue critical for 3-mer-to-3-mer interactions, but not for receptor binding. Despite the predominant functional role of processed BAFF in vivo, membrane-bound BAFF might also play a role. Indeed, soluble BAFF (3-mer) can trigger BAFF-R but not TACI or BCMA, whereas oligomeric forms of BAFF (BAFF 60-mer), which mimic membrane-bound BAFF, activate all BAFF receptors.

NAD Kinase catalytic domain highly active Recombinant Protein

90-352 50 ug
EUR 752.1
Description: NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis.

AXYGEN® AXYPET® PRO 2-20 ΜL SINGLE-CHANNEL PIPETTOR, AUTOCLAVABLE

AP-20-P 1/pk
EUR 242.4
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

20UL FILTER TIPS FOR P-20, RACKED & PRE-STERILIZED

TF-20-R-S 960/pk
EUR 309.6
Description: Filter Tip; Filter Tips Pipette - Axygen

FGF-acidic, Fibroblast Growth Factor-acidic, human

RC215-12 50ug
EUR 183.19

Recombinant Human Fibroblast Growth Factor-acidic

7-00319 10µg Ask for price

Recombinant Human Fibroblast Growth Factor-acidic

7-00320 50µg Ask for price

Recombinant Human Fibroblast Growth Factor-acidic

7-00321 1mg Ask for price

Recombinant Mouse Fibroblast Growth Factor-acidic

7-00325 10µg Ask for price

Recombinant Mouse Fibroblast Growth Factor-acidic

7-00326 50µg Ask for price

Recombinant Mouse Fibroblast Growth Factor-acidic

7-00327 1mg Ask for price

FGF-1/FGF-acidic, human recombinant

4034-10
EUR 164.4

FGF-1/FGF-acidic, human recombinant

4034-1000
EUR 2010

FGF-1/FGF-acidic, human recombinant

4034-50
EUR 307.2

FGF-1/FGF-acidic, murine recombinant

4035-10
EUR 164.4

FGF-1/FGF-acidic, murine recombinant

4035-1000
EUR 2010

FGF-1/FGF-acidic, murine recombinant

4035-50
EUR 307.2
Precautionary resistance administration technique needs to be carried out. The phenomenon described within the examine may have broader organic significance.